
AMIZATE® contains over 120 short peptides. Three of these have been identified and have known bioactivity.
Peptides
Anserine (beta-alanyl-N-methylhistidine) a dipeptide containing β-Alanine and histidine.
Known activity:
- Antioxidantive peptide
- Helps reduce fatigue
Lysine-Proline (Lys-Pro; KP)
Known activity:
- ACE inhibition activity – believed to lower blood pressure
- Antioxidative peptide
Isoleucine / Leucine-Proline (Ile/Leu-Pro; IP/LP)
Known activity:
- ACE inhibition activity – believed to lower blood pressure
- Inhibits the enzyme dipeptidyl-aminopeptidase IV (DPP4 inhibitor) – believed to help people with diabetes
Peptides with biological activities, released during gastrointestinal digestion or food processing, play an important role in metabolic regulation and modulation, suggesting their potential use as nutraceuticals and functional food ingredients for health promotion and disease risk reduction. Many studies have reported that peptides from various food sources possess bioactivities, including antihypertensive, antioxidant, anticancer, antimicrobial and opioid activities as well as immunomodulatory and cholesterol-lowering effects.